Human Brain-Derived Neurotrophic Factor (BDNF) Recombinant Protein 3897S from Cell Signaling Technology

Product Specs
ItemHuman Brain-Derived Neurotrophic Factor (BDNF) Recombinant Protein
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number3897S
Quantity10 µg
Molecule NameBDNF
NCBI Gene AliasesANON2, BULN2
NCBI Full Gene Namebrain derived neurotrophic factor
Research AreaNeuroscience
Molecular Weight27
Source/Expression SystemE. Coli

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 978-867-2388
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Website: http://www.cellsignal.com/

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(1) Risk phenotype for sarcopenia in older adults from Amazonas, Brazil; a cross-sectional studyPLOS ONEOctober 16, 2023Alex Barreto de Lima, Ana Torres-Costoso, Vera Zymbal, Élvio Rúbio Gouveia, Fátima Baptista/body height),16.71±6.03,13.75±5.27,<0.001 Physical Functioning,,, "Physical Activity, MET.min/wk",2663±3897,2024±3131,0.115 "CPF, pts",21.33±3.76,18.41±4.99,<0.001 Sarcopenia Symptoms,,, "SARC-CalF score,

(2) Starvation after infection restricts enterovirus D68 replicationAutophagyJanuary 1, 2023Jassey A, Wagner MA, Galitska G, Paudel B, Miller K, Jackson WT.supplement, glutamax-L (35,050,061), BDNF (brain derived neurotrophic factor; Cell Signaling Technologies, 3897), dibutyryl cAMP (SelleckChem, S7858), penicillin-streptomycin, and trans-retinoic acid. A manuscript

(3) NTF4 plays a dual role in breast cancer in mammary tumorigenesis and metastatic progressionInternational Journal of Biological SciencesJanuary 1, 2023Ran Sun, Jin He, Qin Xiang, Yixiao Feng, Yijia Gong, Yijiao Ning, Chaoqun Deng, Kexin Sun, Mingjun Zhang, Zhaobo Cheng, et al.E-cadherin (#14472, Cell Signaling Technology), N-cadherin (#13116, Cell Signaling Technology), SNAIL (#3897, Cell Signaling Technology), ANXA1 (sc-12740, Santa Cruz), Histone H3 (#4499, Cell Signaling Technology),

(4) Effects of salinity acclimation on histological characteristics and miRNA expression profiles of scales in juvenile rainbow trout (Oncorhynchus mykiss)BMC GenomicsDecember 1, 2022Qi Ling Zhou, Liu Yong Wang, Xiao Long Zhao, Yun Sheng Yang, Qian Ma, Gang Chenexpression modes; the CST miRNAs in Cluster 10, Cluster 11, Cluster 17, Cluster 18 and Cluster 25 each had 3897, 5756, 9423, 8586 and 8977 predicted target genes. Additionally, trend analysis was performed on the

(5) Oxysterol-Binding Protein 2 Promotes Pancreatic Ductal Adenocarcinoma Progression Through Epithelial-Mesenchymal TransitionFrontiers in OncologyJanuary 20, 2022Shuai Huang, Xudong Zhang, Kai Luo, Li Jiang, Jianhua Jiang, Renfeng LiE-cadherin (cat. no. 3195), N-cadherin (cat. no. 13116), Vimentin (cat. no. 5741), Snail (cat. no. 3897), β-catenin (cat. no. 8480), Slug (cat. no. 9585), and ZEB1 (cat. no. 3396) were purchased from Cell Signaling Technology

(6) Curcumin evokes antidepressant-like effects in mice by regulating miR-124/brain derived neurotrophic factorTropical Journal of Pharmaceutical ResearchMay 14, 2021Yanhong Yi, Jing Li, Weian Chen18(3):604 Yi et al Burlington, MA, USA). After blocking, the membranes were incubated with BDNF antibodies (#3897, Cell Signaling Technology, Danvers, MA, USA) at a dilution of 1:1000. The protein bands were detected

(7) Vitamin B12 and estradiol benzoate improve memory retrieval through activation of the hippocampal AKT, BDNF, and CREB proteins in a rat model of multiple sclerosisIran J Basic Med SciMay 6, 2021Narjes Taherian, Gholamhassan Vaezi, Ali Neamati, Leila Etemad, Vida Hojjati, Mahmoud Gorji-Valokolamonoclonal antibodies from Cell Signaling Technology (Beverly, MA, USA): anti-CREB (#4820), anti-BDNF (#3897), anti-AKT (#9272), anti-p-CREB (#9198), anti-p-BDNF (#47808), and anti-p-AKT (#9271) at a concentration

(8) The biophysical basis of receptor tyrosine kinase ligand functional selectivity: Trk-B case studyBiochemical JournalDecember 11, 2020Fozia Ahmed, Michael D. Paul, Kalina Hristovaacceptor concentrations (58). Human brain-derived neurotrophic factor (BDNF, Cell Signaling Technology, 3897S), human neurotrophin-3 (NT-3, Cell Signaling Technology, 5237SC), human neurotrophin-4 (NT-4, Peprotech)

(9) P-Glycoprotein Inhibition Exacerbates Paclitaxel Neurotoxicity in Neurons and Patients With CancerClinical pharmacology and therapeuticsSeptember 1, 2020Stage TB, Mortensen C, Khalaf S, Steffensen V, Hammer HS, Xiong C, Nielsen F, Poetz O, Svenningsen ÅF, Rodriguez-Antona C, et al.(10697623, Fisher Scientific), 1% p/s, 1X Glutamax, 50 ng/ml brain-derived neurotrophic factor (BDNF, CST-3897S, Peprotech), 2 mM dibutyryl cyclic AMP (db-cAMP, D0627 Sigma-Aldrich) and 10 μM RA. Media was replaced

(10) Absence of Glia Maturation Factor Protects from Axonal Injury and Motor Behavioral Impairments after Traumatic Brain InjuryExperimental neurobiologyJune 30, 2020Selvakumar GP, Ahmed ME, Iyer SS, Thangavel R, Kempuraj D, Raikwar SP, Bazley K, Wu K, Khan A, Kukulka K, et al.(UCH-L1; CST, Cat No. 13179S, 1: 800), total and p-NFkB (CST, Cat No. 3033S, 1:800), BDNF (CST, Cat No. 3897S, 1:800), GDNF (CST, Cat No. 3223S, 1:800), iNOS (CST, Cat No. 13120S, 1:800), COX-2(CST, Cat No. 12282S,

(11) Activation of brain‐derived neurotrophic factor signaling in the basal forebrain reverses acute sleep deprivation‐induced fear memory impairmentsBrain and BehaviorApril 1, 2020Tao Ma, Hao Zhang, Zhi‐Peng Xu, Yan Lu, Qiang Fu, Wei Wang, Guan‐Hua Li, Ying‐Ying Wang, Yi‐Tian Yang, Wei‐Dong Micould rescue the deficit of fear memory caused by sleep deprivation (seeFigure 1, Experiment 2). BDNF (#3897, CST) or ANA‐12 (S7745, Sellect.cn) was used to activate or inhibit basal forebrain TrkB signaling,

(12) Epigenetic regulation of microglial phosphatidylinositol 3‐kinase pathway involved in long‐term potentiation and synaptic plasticity in ratsGliaMarch 1, 2020Genevieve Saw, Kumar Krishna, Neelima Gupta, Tuck Wah Soong, Karthik Mallilankaraman, Sreedharan Sajikumar, S. Thameem Dheenwith either active PI3K (1 μg/mL, Cat. No. P27‐18H‐10; SignalChem, USA) or BDNF (200 ng/mL, Cat. No. 3897; Cell Signalling Technologies, USA) 20 min before cells were patched. 2.11 Preparation of hippocampal

(13) Superparamagnetic iron oxide nanoparticles drive miR-485-5p inhibition in glioma stem cells by silencing Tie1 expressionInternational Journal of Biological SciencesFebruary 10, 2020Zhiguang Pan, Yongyi Huang, Haiyang Qian, Xiling Du, Wenxing Qin, Te Liu(#23111),"Cell Signaling Technology, Inc. (Danvers, MA, USA)",IF (1:100)WB(1:1000) Rabbit anti-human BDNF (#3897),"Cell Signaling Technology, Inc. (Danvers, MA, USA)",IF (1:100) WB(1:1000) Rabbit anti-human bFGF

(14) ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathwayNature communicationsJanuary 3, 2020Moskal N, Riccio V, Bashkurov M, Taddese R, Datti A, Lewis PN, Angus McQuibban G.sequential treatment with retinoid acid following by brain-derived neurotrophic factor (Cell Signaling, 3897S)43. Cells were then seeded into white-bottom 96-well plates (CellStar, 655083) and allowed to adhere

(15) 19q13 KRAB zinc-finger protein ZNF471 activates MAPK10/JNK3 signaling but is frequently silenced by promoter CpG methylation in esophageal cancerTheranosticsJanuary 1, 2020Sun R, Xiang T, Tang J, Peng W, Luo J, Li L, Qiu Z, Tan Y, Ye L, Zhang M, et al.E-cadherin (#1702-1; Epitomics), vimentin (#2707-1, Epitomics), N-cadherin (ab98952; Abcam), SNAIL (#3897; Cell Signaling Technology), anti-Flag (#G188; Abm), anti-Flag M2 (#14793; Cell Signaling Technology),

(16) Elevated FAM3C promotes cell epithelial–mesenchymal transition and cell migration in gastric cancerOncoTargets and TherapyDecember 26, 2018Mengyue Shi, Guihua Duan, Shuang Nie, Shanshan Shen, Xiaoping Zoup-Akt (Ser473; CST, 4060), Akt (CST, 2920), p-GSK3β (Ser9; CST, 5558), GSK3β (CST, 12456), Snail (CST, 3897), Slug (CST, 9585), and β-actin (A5441; Sigma-Aldrich). RNA extraction and qRT-PCR Total RNA was isolated

(17) Dimerization of the Trk receptors in the plasma membrane: effects of their cognate ligandsBiochemical JournalNovember 30, 2018Fozia Ahmed, Kalina HristovaCell Signaling Technology, 5221SC), human brain-derived neurotrophic factor (h-BDNF, Cell Signaling Technology, 3897S), or human neurotrophin-3 (hNT-3, Cell Signaling Technology, 5237SC) were added at a concentration of

(18) The novel 19q13 KRAB zinc-finger tumour suppressor ZNF382 is frequently methylated in oesophageal squamous cell carcinoma and antagonises Wnt/β-catenin signallingCell death & diseaseMay 1, 2018Zhang C, Xiang T, Li S, Ye L, Feng Y, Pei L, Li L, Wang X, Sun R, Ren G, et al.E-cadherin (#1702-1, Epitomics), vimentin (#2707-1, Epitomics), N-cadherin (ab98952; Abcam), Snail1 (#3897;Cell Signaling Technology), SLUG (#9585, Cell Signaling Technology), anti-Frizzled homologue 1 antibody

(19) Protective effects of tetrahydropalmatine against ketamine-induced learning and memory injury via antioxidative, anti-inflammatory and anti-apoptotic mechanisms in miceMolecular Medicine ReportsMarch 7, 2018Yonglai Zhang, Rui Sha, Kaiguo Wang, Hao Li, Bo Yan, Naibao Zhou37˚C and then incubated with antibodies against iNOS (13120; 1:2,000), GFAP (12389; 1:2,000), GDNF (3897, 1:2,000), cytochrome c (11940; 1:2,000), PLC‑γ1 (5690; 1:2,000) and GAPDH (5174; 1:1,000; all from

(20) microRNA-664 enhances proliferation, migration and invasion of lung cancer cellsExperimental and Therapeutic MedicineJune 1, 2017Xinhai Zhu, Sheng Ju, Feng Yuan, Guoping Chen, Yue Shu, Chuanchuan Li, Yanhui Xu, Jing Luo, Lilong XiaUSA), and E‑cadherin (3195; 1:1,000), N‑cadherin (13116; 1:3,000), vimentin (5741; 1:3,000), Snail (3897; 1:2,000), AKT (9272; 1:1,000), phosphorylated‑AKT (p‑AKT; 9271; 1:1,000) and phosphatase and tensin

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Human Brain-Derived Neurotrophic Factor (BDNF)

Human Brain-Derived Neurotrophic Factor (BDNF) Recombinant Protein from Cell Signaling Technology

Cell Signaling Technology

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Human Brain-Derived Neurotrophic Factor (BDNF) Recombinant Protein from Cell Signaling Technology

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